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"EFFECT" and "AFFECT"
"Effect" is a noun meaning result. "Affect" is a verb meaning to influence. Ex.: The new policy had a significant effect. The weather can affect our mood.
"LED" and "LEAD"
"Led" is the past tense of the verb "to lead." "Lead" can be a verb meaning to guide or a noun referring to a type of metal. Ex.: She led the team to victory. He will lead the project. The pipes are made of lead.