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"LOSE" and "LOOSE"
"Lose" means to fail to win or misplace. "Loose" means not tight or free. Ex.: I don't want to lose my keys. The button on my shirt is loose.
"LED" and "LEAD"
"Led" is the past tense of the verb "to lead." "Lead" can be a verb meaning to guide or a noun referring to a type of metal. Ex.: She led the team to victory. He will lead the project. The pipes are made of lead.